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Faculty Detail

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Shanna Bowman Assistant Professor

Shanna L Bowman

Assistant Professor


  • B.S., Molecular Biology/Biotechnology, Clarion University
  • Ph.D., Biological Sciences, Carnegie Mellon University
  • Postdoctoral Research Fellow, University of Pennsylvania

Murdock 216


Academic Interests:
My lab researches the cell biology of human skin pigment variation and skin cancer. Specifically, I am interested in melanocortin signaling pathways, which control melanin production and appetite in mammals.


Bowman, S.L., Bi-Karchin, J., Le, L., Marks, M.S. The road to lysosome-related organelles: Insights from Hermansky-Pudlak Syndrome and other rare diseases. Traffic. 2019; 20: 404-435. PMID 30945407

Bowman, S.L., Marks, M.S. Shining a light on black holes in keratinocytes. J Invest Dermatol. 2018; 138: 486-489. PMID 29477191

Crawford, N.G., Kelly, D.*, Hansen, M.E.B.*, Beltrame, M.H.*, Fan, S.*, Bowman, S.L.*, Jewett, E.*, Ranciaro, A., Thompson, S., Yancy, L., Pfeifer, S.P., Jensen, J.D., Campbell, M.C., Beggs, W. Hormozdiari, F., Mpoloka, S.W., Mokone, G., Nyambo, T., Meskel, D.W., Velay, G., Haut, J., NISC Comparative Sequencing Program, Rothschild, H., Zon, L., Zhou, Y., Dovacs, M.A., Xu, M., Zhang, T., Bishop, K. Sinclair, J., Rivas, C., Elliot, E., Choi, J., Li, S.A., Hicks, B., Burgess, S., Abnet, C., Watkins-Chow, D.E., Oceanca, E., Song, Y.S., Eskin, E., Brown, K.M., Marks, M.S., Loftus, S.K., Pavan, W.J., Yeager, M., Chanock, S., Tishkoff, S. Loci associated with skin pigmentation identified in African populations. Science. 2017; 17: 358 (6365). PMID 29025994 (* denotes equal authorship).

Bowman, S.L., Shiwarski, D.J., Puthenveedu, M.A. Distinct G protein-coupled receptor recycling pathways allow spatial control of downstream G protein signaling. J Cell Biol. 2016; 214: 797-806. PMID 27646272.

Tian, X., Irannejad, R., Bowman, S.L., Du, Y., Puthenveedu, M.A., von Zastrow, M., Benovic, J.L. The α-Arrestin ARRDC3 regulates the endosomal residence time and intracellular signaling of the β2-adrenergic receptor. J. Biol. Chem. 2016; 291: 14510-25. PMID 27226565

McGarvey, J.C.,  Xiao, K.H., Bowman, S.L., Mamonova, T., Zhang, Q., Bisello, A., Sneddon, W.B., Ardura, J.A., Jean-Alphonse, F., Vilardaga, J.P., Puthenveedu, M.A., Friedman, P.A. Actin-sorting nexin 27-retromer complex mediates rapid parathyroid hormone receptor recycling. J. Biol. Chem. 2016; 291: 10986-1002. PMID 27008860.

Bowman, S.L.*, Soohoo, A.L.*, Shiwarski, D.J., Schulz, S., Pradhan, A.A., Puthenveedu, M.A. Cell autonomous regulation of mu-opioid receptor recycling by substance P. Cell Reports. 2015; 10: 1925-1936. PMID 25801029. (*denotes equal authorship).

Bowman, S.L., Puthenveedu, M.A. Postendocytic sorting of adrenergic and opioid receptors: new mechanisms and functions, Prog Mol Biol Transl Sci. 2015; 132: 189-206. doi: 10.1016/bs.pmbts.2015.03.005. PMID: 26055059.

Bowman, S.L., Soohoo, A.L., Puthenveedu, M.A. Visualizing and quantitating sequence-dependent GPCR recycling. In W Guo (Ed.). Methods Cell Biol., Sorting and Recycling Endosomes. 2015; 130: 333-345. doi: 10.1016/bs.mcb.2015.05.007. PMID: 263600.

Soohoo, A.L., Bowersox, S.L., Puthenveedu, M.A. Visualizing clathrin-mediated endocytosis of G protein-coupled receptors at single-event resolution via TIRF microscopy. J Vis Exp.2014; 92. doi: 10.3791/51805. PMID: 25350161.

Jean-Alphonse, F., Bowersox, S., Chen, S., Beard, G., Puthenveedu, M.A., Hanyaloglu, A.C. Spatially restricted G protein-coupled receptor activity via divergent endocytic compartments. J. Biol. Chem. 2014; 289: 3960-77. PMID: 24375413.